Humans have a long history of mobility on a spectrum from voluntary migration to forced displacement in response to social, political and environmental change. While many migration drivers exist, climate change is likely to amplify the environmental drivers of migration. At least 1.5°C of warming above pre-industrial levels between 2030 and 2052 are projected if global warming continues to increase at the current rate. The associated impacts are diverse and include temperature and precipitation extremes in most inhabited regions and increased probability of drought and flood. Migration can be an important and useful adaptive response to climate impacts when it increases household resilience and reduces socio-economic vulnerabilities, and yet can also have negative health consequences. The climate–migration–health nexus entails complex interactions including the following: first, climate-related risks to health faced by migrants at all stages of the migration journey. Second, the impacts of migration itself on health with possible specific health implications of climate-related migration. This article provides a brief overview of climate-related migration, identifies climate hotspots where substantial migration and displacement are anticipated and explores the health implications of climate-related migration.